Stem Cell Biology

More than 1.2 million euros for stem cell research into neuronal abnormalities in white matter disorders

European Leukodystrophy Association (ELA) awarded Vivi Heine to study if modulation of Hyaluronan in the host brain microenvironment of a mouse model for Vanishing White Matter Disease (VWM) can improve stem cell therapy.

In this expert review, the challenges for modeling of psychiatric disorders, potential solutions and how induced pluripotent stem cells (iPSC) technology can be used to develop an analytical framework for the evaluation and therapeutic manipulation of fundamental disease processes is evaluated.